After the course the student:
- can relate (epi)genetic variations to brain diseases and traits;
- knows how to run a GWAS;
- can determine the relation between neuronal genes (gene networks and pathways);
- has knowledge of the transcriptome and how to utilize it
- knows the difference and strengths Mendelian versus complex genetic analyses
- has basic knowledge of programming in bioinformatics (R, UNIX).
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Period (from – till): 16 November - 27 November 2020
Course coordinator: Prof.dr. Roger A.H. Adan and Dr K. van Eijk
Faculty
Prof.dr. R.A.H.Adan
Prof.dr. J.P.H. Burbach
Dr. K. van Eijk
Prof dr. J. H. Veldink
Prof. Dr. J.P.H. Burbach
Dr. G. van Gaaften
Dr. O. Basak
Dr. R.M. Brouwer
J. Meier, PhD
M. Bakker
P. Hop
R. Zwamborn
Course description
Every day one lecture followed by hands-on computer practical; each day finishes with a keynote lecture.
During the course there is an assignment with a final presentation (which will be assessed) and an exam.
This course provides an overview of multiple genetic tools used by neuroscientists, including: brain atlases, analysis of pathways and gene sets, GWAS/WebQTL/Phenotype analysis; (single cell) RNAseq, imaging genetics and connectomics.
Central theme: neurological and psychiatric diseases
Literature/study material used
Course Modules (all web-based)
- Expression
- Networks
- Genetics
Registration
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Mandatory for students in Master’s programme
No.
Optional for students in other GSLS Master’s programme:
Yes.
Prerequisite knowledge:
Biomedical Sciences/Biology
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