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Course module: BMB500803
BMB500803
Risk Assessment and Risk Management
Course info
Course codeBMB500803
EC3
Course goals
General objectives
 
The objective of this course is to get acquainted with the principles of risk assessment with the use of all available information from exposure and effect assessment.
 
After completing this course, the student:
  1. is well acquainted with the methods and procedures used in human and environmental health risk assessment.
  2. is able to interpret epidemiological and toxicological study results for use in health risk assessments.
  3. appreciates the differences and linkages between risk assessment, risk management and risk communication.
 
Specific objectives
After completing this course, the student:
  1. has acquired skills to perform risk assessments in specific areas related to chemical exposures
    • for toxicological risk assessment this means that they have acquired knowledge about benchmark dose calculations, in vitro -in vivo extrapolations, route to route extrapolation, the threshold of toxicological concern.
    • for epidemiological risk assessments this means that they have acquired knowledge and are able to perform simple meta-analyses, life table based methods for calculating life-time risks.
  2. has hands-on experience with computer models for estimating exposure and risk.
  3. can apply a  systematic review, including meta‐analytic methods as means primarily of investigating heterogeneities between studies and secondarily as  a means of synthesizing measures of effect.
  4. is able to write a case study on a risk assessment
  5. is able to communicate main concepts of risk assessment to fellow participants.
Content
Period (from – till):  8-19 November 2021

Contact person:
dr. Mieke Lumens (m.lumens@uu.nl) 
 
Lecturer(s):
Name, faculty/department
Prof. dr. D. Heederik, DGK/IRAS/EEPI
Prof dr Juliette Legler, DGK/IRAS
​Prof dr Roel Vermeulen DGK/IRAS
Dr Nynke Kramer, DGK/IRAS
Dr Lutzen Portengen DGK/IRAS
Dr Anke Huss, DGK, IRAS/EEPI
Guest speakers and PhD students

Course content:
To minimize the health effects from exposure to a variety of agents, risk managers and policymakers must be informed by risk assessors who evaluate and summarize the available relevant scientific information. Usually, the available scientific information is limited and far from optimal: data is often scarce, and often only indirectly relevant. Assumptions and uncertainty are therefore two elements that usually typify the risk assessment process. In module 4 it will be shown how the information from exposure assessment (module 1 and 2) and from effect assessment (module 3) may be combined in the framework of a risk assessment. Specific attention will be devoted to examining underlying assumptions, and to dealing with the uncertainties involved.
 
The regulatory aspects of risk assessment will be considered, both on a national and on an international level. Here, focus will be on how risk assessment (science) and risk management (policy) meet, including the non-scientific issues that play a role in practice.

Literature/study material used:
Relevant background information and PowerPoint presentations will be provided.
 
Registration:
You can register for this course via Osiris Student. More information about the registration procedure can be found here on the Studyguide.
Maximum number of participants is 30 students.
 
Mandatory for students in own Master’s programme:
Yes
 
Optional for students in other GSLS Master’s programme:
Yes, only with solid knowledge of exposure science, toxicology and epidemiology
 
Prerequisite knowledge:
Students should have solid knowledge of exposure science, toxicology and environmental epidemiology.
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