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Course module: BMB500803
BMB500803
Risk Assessment and Risk Management
Course info
Course codeBMB500803
EC3
Course goals
After completing this course the student:
  1. has acquired skills to perform risk assessments in specific areas related to chemical exposures:
    • for epidemiological risk assessments this means that they have acquired knowledge and are able to perform simple meta-analyses, life table based methods for calculating life-time risks;
    • for toxicological risk assessment this means that they have acquired knowledge about benchmark dose calculations, in vitro -in vivo extrapolations, route to route extrapolation, the threshold of toxicological concern;
  2. has hands-on experience with computer models for estimating exposure and risk;
  3. can apply a  systematic review, including meta‐analytic methods as means primarily of investigating heterogeneities between studies and secondarily as  a means of synthesizing measures of effect;
  4. is able to handle a case study on a risk assessment and to communicate this to fellow-participants;
  5. is familiar with the main principles of good risk communication and determinants of risk perception.
Content
Period (from – till): 7 November 2016 - 18 November 2016
 
Lecturer(s):
Prof. dr. D. Heederik, DGK/IRAS/EEPI
E D.Heerik@uu.nl
T 030-2539480,
Dr Nynke Kramer, IRAS/TOX
Dr Anke Huss, DGK, IRAS/EEPI
Guest speakers and PhD students

Course content
To minimize the health effects from exposure to a variety of agents, risk managers and policymakers must be informed by risk assessors who evaluate and summarize the available relevant scientific information. Usually, the available scientific information is limited and far from optimal: data is often scarce, and often only indirectly relevant. Assumptions and uncertainty are therefore two elements that usually typify the risk assessment process. In module 4 it will be shown how the information from exposure assessment (module 1 and 2) and from effect assessment (module 3) may be combined in the framework of a risk assessment. Specific attention will be devoted to examining underlying assumptions, and to dealing with the uncertainties involved.

The regulatory aspects of risk assessment will be considered, both on a national and on an international level. Here, focus will be on how risk assessment (science) and risk management (policy) meet, including the non-scientific issues that play a role in practice.

Literature/study material used:
A reader with relevant background information and PowerPoint presentations will be provided.

Registration:
Apply via the studyguide.

Mandatory:
TXEH students

Optional for students in other GSLS Master’s programme:
Yes

Prerequisite knowledge:
Students should have a BSc in Biology, Biomedical Sciences, Medicine, Veterinary Medicine, Pharmacy or Environmental Sciences.
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