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Course module: BMB436006
BMB436006
Cell Organisation in Health and Disease
Course info
Course codeBMB436006
ECTS Credits1.5
Category / LevelM (Master)
Course typeCourse
Language of instructionEnglish
Offered byFaculty of Medicine; Graduate School of Life Sciences; Cancer, Stem Cells and Development Biology;
Contact personM.M. Maurice
E-mailm.m.maurice@umcutrecht.nl
Teaching period
MASTER  (21/08/2017 to 18/08/2018)
Teaching period in which the course begins
MASTER
Time slot-: Not in use
Study mode
Full-time
Remarkdate 12-16 march 2018 Apply via www.CSnD.nl
Course application processadministratie onderwijsinstituut
Enrolling through OSIRISNo
Enrolment open to students taking subsidiary coursesNo
Pre-enrolmentNo
Waiting listNo
Course placement processadministratie onderwijsinstituut
Course goals
At the end of the course the student:
  1. knows the state-of-the-art strategies and techniques used in membrane traffic research;
  2. knows the possibilities offered in the field of membrane traffic research;
  3. has advanced knowledge of membrane traffic and its relationship to disease and development;
  4. can use this knowledge to read series of articles on a given subject and produce integrated view onhow the studied membrane traffic defect explains the etiology of the disease or developmental defect;
  5. is able to participate in scientific discussions;
  6. is able to analyse presentations of other scientist.
Content
Period (from – till): 12 March 2018 - 16 March 2018.
 
Faculty
dr. Madelon Maurice
Prof. Dr. Judith Klumperman
dr. Peter vd Sluijs
dr. Catherine Rabouille
Prof.dr. Willem Stoorvogel
Invited speaker (international)
 
Description of content
The purpose of this Master Class has two aspects:
-Acquire basic and advanced knowledge on membrane traffic and its relationship to disease and development.
-Use this knowledge to read a series of articles on a given subject and produce an integrated view of how the studied membrane traffic defect (due to a given mutation) explains the etiology of the disease or the developmental defect.

Course organization:
- 20 students (max) will receive training in reading and interpreting scientific literature dealing with membrane traffic in disease and development.

- First, the students get 5 introductory lectures on the relationship between different aspects of membrane traffic with diseases and development by Judith Klumperman, Peter van der Sluijs, Catherine Rabouille, Willem Stoorvogel and Madelon Maurice.
-The students are divided in 5 groups and assigned a given subject that they will prepare so at the end of this week, the students are expected to: 1) provide a concise and coherent oral presentation of research papers in a format of a journal club 20 min, including 10 min discussion combining several papers (see guidelines) given by the teachers. The presentation will have to integrate the data of these papers to make a single and cohesive story while presenting primary data (see guidelines). This is an important research exercise, so you learn to read, integrate information and write an introduction, a review, a thesis, etc.
2) After the final presentation on Friday, there will be an exam: students will be asked to answer questions about all subjects (5 in total) for 1 hour. Thus it is important that the students gather sufficient information during the presentation of fellow students. The exam also drives all participants into presenting the best you can so that others can understand.

Further remarks: The week is meant to be dedicated to this course. The students have to be together all the time, either as a small or large group. The preparation of the presentation and the research proposal has to be made together as a small group to start with. Thursday, however, is dedicated to rehearse the presentation and improve it with all fellow students of the course who do not deal with the same subject but who will critically evaluate and ask questions to improve the talks.
Grades: The grade will be based on performance during the week (interest, participation 20%), the presentation itself (with individual marks of students for presentation and discussion 40%), and the exam at the end (40%)

Literature/study material used:
varies according to assignments

Registration:
www.CSnD.nl/courses

Mandatory for students in own Master’s programme:
No

Optional for students in other GSLS Master’s programme:
Yes

Prerequisite knowledge:
Bsc BMW / Biology
Entry requirements
Prerequisite knowledge
Although basic mechanisms will be integrated in the teaching, the course is best suited for students that have a basic molecular understanding of subcellular organization through textbooks such as Molecular Biology of the Cell (Alberts).
Required materials
-
Instructional formats (attendance required)
Core lecture (Required)

Lecture (Required)

Presentation (Required)

Private-study (Required)

Seminar (Required)

Tests
Eindresultaat
Test weight100
Minimum grade5.5

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