After completing the course, students are able to:
- Demonstrate theoretical knowledge on:
- Chromatographic separation and purification techniques: TLC, GLC
- Spectroscopic identification techniques such as UV/Vis, IR, NMR
- Lipids, their structure, their properties, their functions in the chemistry of life
- Potentiometry: an electroanalytical technique
- Mechanistic concepts in organic chemistry
- Through supporting lectures and/or self-study from textbooks,
- Demonstrate basic practical skills in:
- Organic synthesis
- Purification techniques such as recrystallization and distillation
- Separation techniques such as TLC, GC
- Spectroscopic identifications with UV/Vis, IR and NMR
- Analytical techniques such as Potentiometry (ISE)
- Demonstrate laboratory safety
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In this course you experience the omnipresence of chemical sciences in life. You are exposed to a broad set of practical chemical experiments, illustrating the applications and possibilities of different chemical methods: the making of chemicals, the purification, characterization and quantification of what you create, and understanding the theory and mechanisms behind it. You create a set of dyes and study its application, synthesize your own aspirin and test its purity and quality, you will check commercial toothpastes for its fluoride content and do a lipid analysis of foodstuff (oils) and understand the methods you used for these analyses. Finally, you study a chemical conversion reaction and try to reveal the mechanism behind it by looking at the product composition.
Format
- lectures
- self study
- practicals:
- Synthesis of Organic
- Dyes and applications in dyeing fabrics
- Synthesis of the drug Aspirin and quality control of your product
- Testing the Fluoride content in commercial Toothpaste (Potentiometry – ISE)
- Basics of chromatographic separation and purification techniques (GC, TLC)
- Characterization and quantification of Lipids in edible oils using GC.
- Mechanistic concepts in synthetic organic chemistry and product formation (Alkene formation by dehydration of alcohols, a spectroscopic challenging experience!)
Attendance
Due to the short duration and intensive nature of the lab course, 100% attendance is required.
Contact: Stephan Jonker, s.a.jonker@uu.nl, 030 253 7662
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